3-Nitrobenzoic acid → N-[3-(methylsulfanyl)phenyl]-3-nitrobenzamide

반응식

[CH3:1][S:2][C:3]1[CH:4]=[C:5]([CH:7]=[CH:8][CH:9]=1)[NH2:6].[N+:10]([C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][CH:21]=1)[C:16](O)=[O:17])([O-:12])=[O:11]>>[N+:10]([C:13]1[CH:14]=[C:15]([CH:19]=[CH:20][CH:21]=1)[C:16]([NH:6][C:5]1[CH:7]=[CH:8][CH:9]=[C:3]([S:2][CH3:1])[CH:4]=1)=[O:17])([O-:12])=[O:11]

참가 물질

반응물 2

HCID 84973-Nitrobenzoic acid

HCID 15693Benzenamine, 3-(methylthio)-

생성물 1

HCID 895917N-[3-(methylsulfanyl)phenyl]-3-nitrobenzamide수율 94.6%

실험 절차

Using 3-methylthioaniline (2.1 ml, 16.5 mmol) and 3-nitrobenzoic acid (2.64 g, 15.0 mmol), the procedure of Reference Example 16 was repeated to obtain 4.09 g (94.6%) of the title compound in the form of light yellow needle crystals.

출처 및 근거

ORD 기록: ord-c16cf1c3e2df4892b6f3150e9b21bcaf
출처 데이터셋: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05728835

반응 노트

불러오는 중…