Ethyl propiolate → Ethyl 1H-1,2,3-triazole-5-carboxylate

HRID 244663노트

반응식

HRID 244663 반응식
[C:1]([O:5][CH2:6][CH3:7])(=[O:4])[C:2]#[CH:3].C[Si]([N:12]=[N+:13]=[N-:14])(C)C>CO>[N:12]1[NH:13][N:14]=[C:2]([C:1]([O:5][CH2:6][CH3:7])=[O:4])[CH:3]=1

참가 물질

4

반응물 2

HCID 12182Ethyl propiolateHCID 78378Azidotrimethylsilane

생성물 1

HCID 6419107Ethyl 1H-1,2,3-triazole-5-carboxylate

시약·촉매·용매 1

HCID 887Methanol용매

반응 조건

온도
100 °C

실험 절차

A mixture of ethyl 2-propynoate (4.13 ml) and trimethylsilyl azide (13.5 ml) was heated to 100° C. for 24 h. The cooled mixture was cautiously decomposed with methanol (50 ml) and evaporated in vacuo to give the title compound (5.7 g) as a white solid.

후처리

  1. customevaporated in vacuo

출처 및 근거

ORD 기록
ord-17cd3a618aeb453abdda756edd026a5b
출처 데이터셋
uspto-grants-2014_02
특허 번호
US08658635B2

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