Sulfuric Acid → HCID 22238302, 화합물

HRID 244762

반응식

HRID 244762 반응식
[CH2:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:9][CH3:10])[CH3:2].[C:11](Cl)(=[O:14])[CH2:12][CH3:13].[Al+3].[Cl-:17].[Cl-].[Cl-].S(=O)(=O)(O)O>[N+](C)([O-])=O>[Cl:17][CH2:13][CH2:12][C:11]([C:7]1[CH:6]=[CH:5][C:4]([CH2:9][CH3:10])=[C:3]([CH2:1][CH3:2])[CH:8]=1)=[O:14]

참가 물질

6

반응물 4

HCID 1118Sulfuric AcidHCID 86571,2-DiethylbenzeneHCID 62324Propionyl chlorideHCID 6451240Aluminum(III) Chloride

생성물 1

HCID 22238302HCID 22238302, 화합물

시약·촉매·용매 1

HCID 6375Nitromethane용매

실험 절차

1,2-Diethylbenzene (10.9 g, 74.6 mmol) and propionyl chloride (9.7 g, 74.6 mmol) are added dropwise to AlCl3 (22.3 g, 167.8 mmol) in nitromethane (75 mL) over 30 min. The reaction mixture is stirred at room temperature for 2 hours, after which 70 g of ice and 14 mL concentrated sulphuric acid are added. The aqueous phase is extracted with ether, and the combined organic phases extracted with 2N HCl and saturated aqueous NaCl. The organic phase is further treated with activated charcoal, magnesium sulphate, and filtered, and the solvent removed in vacuo.

후처리

  1. extractionThe aqueous phase is extracted with ether
  2. extractionthe combined organic phases extracted with 2N HCl and saturated aqueous NaCl
  3. additionThe organic phase is further treated with activated charcoal, magnesium sulphate
  4. filtrationfiltered
  5. customthe solvent removed in vacuo

출처 및 근거

ORD 기록
ord-d49820e5415d42d08eeba64a59216717
출처 데이터셋
uspto-grants-2014_02
특허 번호
US08658673B2

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