Acetic Anhydride → 1-Acetylindolin-2-one

HRID 24724

반응식

HRID 24724 반응식
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][C:2]1=[O:10].[C:11](OC(=O)C)(=[O:13])[CH3:12]>>[C:11]([N:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][C:2]1=[O:10])(=[O:13])[CH3:12]

참가 물질

3

반응물 2

HCID 7918Acetic AnhydrideHCID 321710Oxindole

생성물 1

HCID 3237191-Acetylindolin-2-one

실험 절차

13.3 g (0.1 mol) of 2-indolinone and 30 ml of acetic anhydride are stirred for 3 hours at 170° C. After cooling, 150 ml of ice water are added, the crystalline product is suction filtered, washed with water and dried.

후처리

  1. temperatureAfter cooling
  2. filtrationfiltered
  3. washwashed with water
  4. customdried

출처 및 근거

ORD 기록
ord-76ea57a045934b3084c0c2d4c7aabd87
출처 데이터셋
uspto-grants-2005_02
특허 번호
US06855710B2

연결된 노트

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