Benzene, (triethoxymethyl)- → 1-Acetyl-3-(1-ethoxy-1-phenylmethylidene}-2-indolinone

HRID 24725

반응식

HRID 24725 반응식
[C:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH2:6][C:5]1=[O:13])(=[O:3])[CH3:2].[CH3:14][CH2:15][O:16][C:17](OCC)(OCC)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>C(OC(=O)C)(=O)C>[C:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[C:17]([O:16][CH2:15][CH3:14])[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:5]1=[O:13])(=[O:3])[CH3:2]

참가 물질

4

반응물 2

HCID 74268Benzene, (triethoxymethyl)-HCID 3237191-Acetylindolin-2-one

생성물 1

HCID 542378881-Acetyl-3-(1-ethoxy-1-phenylmethylidene}-2-indolinone

시약·촉매·용매 1

HCID 7918Acetic Anhydride용매

실험 절차

35.0 g (0.2 mol) of 1-acetyl-2-indolinone are dissolved in 300 ml of acetic anhydride and after the addition of 135 g (0.6 mol) of triethyl orthobenzoate the mixture is refluxed for 22 hours. The solvent is distilled off and the residue diluted with petroleum ether. After 18 hours' standing at ambient temperature, the crystalline precipitate is suction filtered, washed and dried.

후처리

  1. temperatureis refluxed for 22 hours
  2. distillationThe solvent is distilled off
  3. additionthe residue diluted with petroleum ether
  4. filtrationfiltered
  5. washwashed
  6. customdried

출처 및 근거

ORD 기록
ord-9cad90a0f5794d64b7d4ec75067742a0
출처 데이터셋
uspto-grants-2005_02
특허 번호
US06855710B2

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