Ethanol → 3-(1-Ethoxy-1-phenyl-methylidene)-2-indolinone

HRID 24740노트

반응식

HRID 24740 반응식
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[C:13]([O:20][CH2:21][CH3:22])[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:5]1=[O:23])(=O)C.C(O)C.[OH-].[Na+]>O>[CH2:21]([O:20][C:13](=[C:6]1[C:7]2[C:12](=[CH:11][CH:10]=[CH:9][CH:8]=2)[NH:4][C:5]1=[O:23])[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)[CH3:22]

참가 물질

5

반응물 3

HCID 702EthanolHCID 14798Sodium HydroxideHCID 542378881-Acetyl-3-(1-ethoxy-1-phenylmethylidene}-2-indolinone

생성물 1

HCID 540376233-(1-Ethoxy-1-phenyl-methylidene)-2-indolinone

시약·촉매·용매 1

HCID 962Water용매

실험 절차

6.15 g (20 mmol) of 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-2-indolinone are suspended in a little ethanol. 10 ml of 4N sodium hydroxide solution are added and the mixture is stirred for 1.5 hours at ambient temperature. After the addition of 100 ml of water the precipitate is suction filtered, washed with water and a little ether and dried at 80° C.

후처리

  1. filtrationfiltered
  2. washwashed with water
  3. dry with materiala little ether and dried at 80° C.

출처 및 근거

ORD 기록
ord-2873a7ec518c40c286dc86ec59daace2
출처 데이터셋
uspto-grants-2005_02
특허 번호
US06855710B2

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