Sodium Hydroxide → 3-(1-Ethoxy-1-phenyl-methylidene)-2-indolinone

HRID 24767노트

반응식

HRID 24767 반응식
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[C:13]([O:20][CH2:21][CH3:22])[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:5]1=[O:23])(=O)C.[OH-].[Na+]>C(O)C.O>[CH2:21]([O:20][C:13](=[C:6]1[C:7]2[C:12](=[CH:11][CH:10]=[CH:9][CH:8]=2)[NH:4][C:5]1=[O:23])[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)[CH3:22]

참가 물질

5

반응물 2

HCID 14798Sodium HydroxideHCID 542378881-Acetyl-3-(1-ethoxy-1-phenylmethylidene}-2-indolinone

생성물 1

HCID 540376233-(1-Ethoxy-1-phenyl-methylidene)-2-indolinone

시약·촉매·용매 2

HCID 702Ethanol용매HCID 962Water용매

실험 절차

4.0 g (13.2 mmol) of 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-2-indolinone are suspended in 50 ml of ethanol and after the addition of 10 ml of 4N sodium hydroxide solution stirred for 90 minutes at ambient temperature. The solution is diluted with 150 ml of water, the crystalline product is suction filtered, washed and dried.

후처리

  1. filtrationfiltered
  2. washwashed
  3. customdried

출처 및 근거

ORD 기록
ord-18b3187e488642c0a3b625cd6c1e19ec
출처 데이터셋
uspto-grants-2005_02
특허 번호
US06855710B2

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