Styrene → Ethyl 2-phenylcyclopropane-1-carboxylate

HRID 247736노트

반응식

HRID 247736 반응식
[N+](=[CH:3][C:4]([O:6][CH2:7][CH3:8])=[O:5])=[N-].[CH2:9]=[CH:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>C(Cl)Cl>[C:11]1([CH:10]2[CH2:9][CH:3]2[C:4]([O:6][CH2:7][CH3:8])=[O:5])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

참가 물질

4

반응물 2

HCID 7501StyreneHCID 12192Ethyl diazoacetate

생성물 1

HCID 316914Ethyl 2-phenylcyclopropane-1-carboxylate

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

The reaction described in Example 3 was substantially repeated except that the Cu,K-PFIEP[SO3H] catalyst was replaced by the Cu,K-PFIEP[SO3H]/PFIEP[CO2H] (0.58 g) catalyst described above. The reaction mixture was allowed to stir for 0.5 hour after the addition of the solution of ethyl diazoacetate, CH2Cl2 and styrene. Analysis by gas chromatography showed that the combined yield of cis- and trans-ethyl-2-phenylcyclopropanecarboxylates was 95%.

출처 및 근거

ORD 기록
ord-bb2afe9230064bc1a80c9c13c0ac85ec
출처 데이터셋
uspto-grants-1987_11
특허 번호
US04709085

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