Hydrochloric Acid → 6-(Decyloxy)naphthalen-2-ol

HRID 247797

반응식

HRID 247797 반응식
[CH2:1](Br)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[OH:12][C:13]1[CH:22]=[CH:21][C:20]2[C:15](=[CH:16][CH:17]=[C:18]([OH:23])[CH:19]=2)[CH:14]=1.C(=O)([O-])[O-].[K+].[K+].Cl>CN(C)C=O.O.C(OCC)C>[CH2:1]([O:12][C:13]1[CH:22]=[CH:21][C:20]2[C:15](=[CH:16][CH:17]=[C:18]([OH:23])[CH:19]=2)[CH:14]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

참가 물질

8

반응물 4

HCID 313Hydrochloric AcidHCID 81731-BromodecaneHCID 11430Potassium CarbonateHCID 935522,6-Dihydroxynaphthalene

생성물 1

HCID 145735486-(Decyloxy)naphthalen-2-ol수율 53.3%

시약·촉매·용매 3

HCID 962Water용매HCID 3283Diethyl Ether용매HCID 6228Dimethylformamide용매

실험 절차

A solution of decylmonobromide (1.5 g), 2,6-dihydroxynaphthalene (1 g) and anhydrous potassium carbonate (0.8 g) in dimethylformamide (50 ml) was stirred at 130° C. for four hours. The solution was poured in water and was made neutral with dilute aqueous hydrochloric acid solution. To the solution was added diethyl ether in order to effect extraction and the extract was distilled to remove the solvent. The residue was washed with hexane and recrystallized from water/ethanol (1/9) to obtain the titled compound (about 1 g).

후처리

  1. extractionextraction
  2. distillationthe extract was distilled
  3. customto remove the solvent
  4. washThe residue was washed with hexane
  5. customrecrystallized from water/ethanol (1/9)

출처 및 근거

ORD 기록
ord-3dc937dc4f61493886c7a97501948512
출처 데이터셋
uspto-grants-1993_05
특허 번호
US05207947

연결된 노트

불러오는 중…