Methyl iodide → 2-[[Acetyl[4-methoxy-3-(tetradecyloxy)benzoyl]-amino]methyl]-1-methylpyridinium iodide

HRID 247954노트

반응식

HRID 247954 반응식
[C:1]([N:4]([CH2:30][C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][N:32]=1)[C:5](=[O:29])[C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[CH:7]=1)(=[O:3])[CH3:2].[CH3:37][I:38]>>[I-:38].[C:1]([N:4]([CH2:30][C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][N+:32]=1[CH3:37])[C:5](=[O:29])[C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[CH:7]=1)(=[O:3])[CH3:2]

참가 물질

3

반응물 2

HCID 6328Methyl iodideHCID 10255296N-Acetyl-4-methoxy-3-(tetradecyloxy)-N-(2-pyridinylmethyl)benzamide

생성물 1

HCID 99865782-[[Acetyl[4-methoxy-3-(tetradecyloxy)benzoyl]-amino]methyl]-1-methylpyridinium iodide

실험 절차

The title compound is prepared by the procedure of Example 28 using 0.421 g of product from Example 44 and 2.64 ml of methyl iodide. The residue is recrystallized from methyl alcohol to give 0.541 g of the desired product as yellow crystals.

후처리

  1. customThe residue is recrystallized from methyl alcohol

출처 및 근거

ORD 기록
ord-d82f648136a246afa44f21bfb38a1b47
출처 데이터셋
uspto-grants-1993_05
특허 번호
US05208247

반응 노트

불러오는 중…