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4-Nitrophenol → 4-Nitrophenyl tetradecyl ether

HRID 247989
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인쇄 미리보기

반응식

HRID 247989 반응식
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[CH:6][CH:5]=1)([O-:3])=[O:2].Br[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25].[OH-].[Na+].C1(C)C=CC=CC=1>[Cl-].C([N+](CCCCCCCC)(CCCCCCCC)C)CCCCCCC.O>[CH2:25]([O:10][C:7]1[CH:8]=[CH:9][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=1)[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH3:12]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

7

반응물 4

HCID 9804-NitrophenolHCID 1140TolueneHCID 8208Myristyl bromideHCID 14798Sodium Hydroxide

생성물 1

HCID 103370514-Nitrophenyl tetradecyl ether

시약·촉매·용매 2

HCID 21218Trioctylmethylammonium chloride촉매
HCID 962
Water
용매

실험 절차

A mixture of 75 g of 4-nitrophenol, 149.5 g of 1-bromotetradecane, 26.96 g of sodium hydroxide, 2.18 g of trioctyl methylammonium chloride, 400 ml of toluene and 400 of water is heated at reflux for 65 hours. The organic layer is separated, washed with 1N sodium hydroxide and dilute hydrochloric acid, dried and concentrated in vacuo. The residue is recrystallized from petroleum ether to give the desired product.

후처리

  1. temperatureis heated
  2. temperatureat reflux for 65 hours
  3. customThe organic layer is separated
  4. washwashed with 1N sodium hydroxide and dilute hydrochloric acid
  5. customdried
  6. concentrationconcentrated in vacuo
  7. customThe residue is recrystallized from petroleum ether

출처 및 근거

ORD 기록
ord-a4c6f5b05695488490e9ebe1e9f8dbc1
출처 데이터셋
uspto-grants-1993_05
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US05208247

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