Sodium Hydroxide → HCID 178453075, 화합물

HRID 24828

반응식

HRID 24828 반응식
C([N:4]1[C:12]2[C:7](=[CH:8][C:9]([N+:13]([O-:15])=[O:14])=[CH:10][CH:11]=2)[C:6](=[C:16](OCC)[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:5]1=[O:26])(=O)C.[C:27]([O:31][C:32]([NH:34][CH2:35][C:36]1[CH:42]=[CH:41][C:39]([NH2:40])=[CH:38][CH:37]=1)=[O:33])([CH3:30])([CH3:29])[CH3:28].[OH-].[Na+]>CN(C=O)C.CO>[C:27]([O:31][C:32]([NH:34][CH2:35][C:36]1[CH:42]=[CH:41][C:39]([NH:40]/[C:16](=[C:6]2\[C:5](=[O:26])[NH:4][C:12]3[C:7]\2=[CH:8][C:9]([N+:13]([O-:15])=[O:14])=[CH:10][CH:11]=3)/[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:38][CH:37]=1)=[O:33])([CH3:30])([CH3:28])[CH3:29]

참가 물질

6

반응물 3

HCID 14798Sodium HydroxideHCID 2756041tert-butyl N-[(4-aminophenyl)methyl]carbamateHCID 542801041-Acetyl-3-{1-ethoxy-1-phenylmethylidene}-5-nitro-2-indolinone

생성물 1

HCID 178453075HCID 178453075, 화합물

시약·촉매·용매 2

HCID 887Methanol용매HCID 6228Dimethylformamide용매

실험 절차

Prepared analogously to Example 82 from 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-5-nitro-2-indolinone and 4-tert.butoxycarbonylaminomethyl-aniline in DMF and subsequent treatment with sodium hydroxide solution in methanol.

출처 및 근거

ORD 기록
ord-cbfbc54cff7e4c43a14266785e577960
출처 데이터셋
uspto-grants-2005_02
특허 번호
US06855710B2

연결된 노트

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