Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-5-methylthiazole → 2-(2,3-Dihydro-2-imino-5-methyl-3-thiazolyl)-1-(2-thienyl)ethanone hydrobromide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-5-methylthiazole | HCID 351770 | — |
| 반응물 | 2-Bromo-1-(thiophen-2-yl)ethan-1-one | HCID 2776372 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | 2-(2,3-Dihydro-2-imino-5-methyl-3-thiazolyl)-1-(2-thienyl)ethanone hydrobromide | HCID 22401741 | — |
반응 단계
A mixture of 51 parts of 2-bromo-1-(2-thienyl)ethanone, 28.5 parts of 5-methyl-2-thiazolamine and 240 parts of acetonitrile was stirred for 1 hour while heating on a waterbath. After cooling, the precipitate was filtered off, washed with ethanol and dried in vacuo, yielding 54 parts of 2-(2,3-dihydro-2-imino-5-methyl-3-thiazolyl)-1-(2-thienyl)ethanone hydrobromide; mp. 207.5°-208° C. (interm. 56).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05212192 |
| 출처 데이터셋 | uspto-grants-1993_05 |
| ORD ID | ord-ada5bbdbe62d4290905705d5d577da87 |
| 출처 메모 | uspto-grants-1993_05 |