Dimethylamine → N,N-dimethyl-2-(4-nitrophenoxy)ethanamine

HRID 24937

반응식

HRID 24937 반응식
Br[CH2:2][CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[CH:7][CH:6]=1.[CH3:14][NH:15][CH3:16]>CN(C)C=O>[CH3:14][N:15]([CH3:16])[CH2:2][CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[CH:7][CH:6]=1

참가 물질

4

반응물 2

HCID 674DimethylamineHCID 2359871-(2-Bromoethoxy)-4-nitrobenzene

생성물 1

HCID 887421N,N-dimethyl-2-(4-nitrophenoxy)ethanamine

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

4.9 g (20 mmol) of 4-(2-bromoethyloxy)-nitrobenzene and 2.7 g (60 mmol) of dimethylamine in 50 ml of dimethylformamide are heated to 100° C. for 24 hours in a bomb tube. After removal of the solvent in vacuo the residue is taken up in water and extracted with dichloromethane. The organic phase is dried and concentrated by evaporation.

후처리

  1. customAfter removal of the solvent in vacuo the residue
  2. extractionextracted with dichloromethane
  3. customThe organic phase is dried
  4. concentrationconcentrated by evaporation

출처 및 근거

ORD 기록
ord-a8e4bf5abd1e4934998ac18b605dab70
출처 데이터셋
uspto-grants-2005_02
특허 번호
US06855710B2

연결된 노트

불러오는 중…