N,N,2-trimethyl-3-nitroaniline → 1-N,1-N,2-trimethylbenzene-1,3-diamine

HRID 24980노트

반응식

HRID 24980 반응식
[CH3:1][N:2]([CH3:13])[C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([N+:9]([O-])=O)[C:4]=1[CH3:12]>CO.[H][H].[Ni]>[CH3:1][N:2]([CH3:13])[C:3]1[C:4]([CH3:12])=[C:5]([CH:6]=[CH:7][CH:8]=1)[NH2:9]

참가 물질

5

반응물 1

HCID 22225799N,N,2-trimethyl-3-nitroaniline

생성물 1

HCID 111373411-N,1-N,2-trimethylbenzene-1,3-diamine수율 93.7%

시약·촉매·용매 3

HCID 935Nickel촉매HCID 887Methanol용매HCID 178418361HCID 178418361, 화합물용매

실험 절차

73 g of N,N-dimethyl-2-methyl-3-nitroaniline are dissolved in 800 ml of methanol and hydrogenated at 20° C. under 5 bar of hydrogen using Raney nickel as catalyst. 57 g of 3-dimethylamino-2-methylaniline are obtained.

출처 및 근거

ORD 기록
ord-777aafa5e9a347c983e7b8043409261a
출처 데이터셋
uspto-grants-2005_02
특허 번호
US06858594B2

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