Citraconic Anhydrides → 3-BroMo-4-Methylfuran-2,5-dione

HRID 249990

반응식

HRID 249990 반응식
[CH3:1][C:2]1[C:3](=[O:8])[O:4][C:5](=[O:7])[CH:6]=1.[Al](Br)(Br)[Br:10].BrBr>C(OCC)(=O)C>[Br:10][C:6]1[C:5](=[O:7])[O:4][C:3](=[O:8])[C:2]=1[CH3:1]

참가 물질

5

반응물 3

HCID 12012Citraconic AnhydridesHCID 24408BromineHCID 24409Aluminum bromide

생성물 1

HCID 105838543-BroMo-4-Methylfuran-2,5-dione수율 9,023.2%

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

반응 조건

온도
120 °C

실험 절차

A mixture of 3-methyl-2,5-furandione (citraconic anhydride, 1 g), AlBr3 (26 mg) and Br2 (0.46 mL) was heated at 120° C. overnight. Ethyl acetate was then added and the organic phase was washed with HCl 0.1% and then with brine. The organic phase was dried and concentrated in vacuo to give the crude product (1.680 g) that was used without further purification.

후처리

  1. washthe organic phase was washed with HCl 0.1%
  2. customThe organic phase was dried
  3. concentrationconcentrated in vacuo

출처 및 근거

ORD 기록
ord-7740d3fce82847729128eaba9969fa7f
출처 데이터셋
uspto-grants-2011_01
특허 번호
US07863299B2

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