Hydrochloric Acid → 3-Pyridinecarboxylic acid, 6-(4-amino-1-piperidinyl)-, ethyl ester
반응식
C(OC([NH:8][CH:9]1[CH2:14][CH2:13][N:12]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([O:23][CH2:24][CH3:25])=[O:22])=[CH:17][N:16]=2)[CH2:11][CH2:10]1)=O)(C)(C)C.Cl>C(OCC)(=O)C>[NH2:8][CH:9]1[CH2:14][CH2:13][N:12]([C:15]2[CH:20]=[CH:19][C:18]([C:21]([O:23][CH2:24][CH3:25])=[O:22])=[CH:17][N:16]=2)[CH2:11][CH2:10]1참가 물질
4
실험 절차
The product of stage b) is dissolved in ethyl acetate, a 3N solution of hydrochloric acid in ethyl acetate is added and the mixture is left stirring at ambient temperature for 10 hours. The product is filtered off and washed with acetone. The title product is obtained. M.p.: 148-150° C.
후처리
- waitthe mixture is left
- filtrationThe product is filtered off
- washwashed with acetone
출처 및 근거
- ORD 기록
- ord-007fab9badaf4c7ca8c9d853d77769da
- 출처 데이터셋
- uspto-grants-2005_02
- 특허 번호
- US06858629B1
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