Hydrochloric Acid → HCID 66887928, 화합물

HRID 252379

반응식

HRID 252379 반응식
[CH3:1][O:2][C:3](=[O:13])[C:4]([CH3:12])([C:6]1[CH:7]=[N:8][CH:9]=[CH:10][CH:11]=1)[CH3:5].[ClH:14]>CO.O.[Pt](=O)=O>[ClH:14].[CH3:1][O:2][C:3](=[O:13])[C:4]([CH3:5])([CH:6]1[CH2:11][CH2:10][CH2:9][NH:8][CH2:7]1)[CH3:12]

참가 물질

5

반응물 2

HCID 313Hydrochloric AcidHCID 54537815HCID 54537815, 화합물

생성물 1

HCID 66887928HCID 66887928, 화합물

시약·촉매·용매 2

HCID 11139377Platinum dioxide monohydrate촉매HCID 887Methanol용매2회

실험 절차

A mixture of 0.823 g of 2-methyl-2-pyridin-3-yl-propionic acid methyl ester [476429-23-9] and 0.062 g of platinum(IV) oxide hydrate in 8 ml of methanol and 1.7 ml of 1.2M HCl in methanol at room temperature is hydrogenated for 5.5 hours. The catalyst is removed by filtration over Hyflo and the filtrate is concentrated by evaporation to provide the crude title compound as a brown oil which is used in the next step without further purification.

후처리

  1. customThe catalyst is removed by filtration over Hyflo
  2. concentrationthe filtrate is concentrated by evaporation

출처 및 근거

ORD 기록
ord-6d202131da254efb96a29d25c4b84ec3
출처 데이터셋
uspto-grants-2011_01
특허 번호
US07868036B2

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