Hydrochloric Acid → Triethylammonium 1,1,3,3,3-pentafluoro-2-(benzoyloxy)propanesulfonate

HRID 252900

반응식

HRID 252900 반응식
[CH2:1]([N:3]([CH2:6][CH3:7])[CH2:4][CH3:5])[CH3:2].Cl.[F:9][C:10]([F:29])([S:25]([O-:28])(=[O:27])=[O:26])[CH:11]([O:16][C:17](=[O:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:12]([F:15])([F:14])[F:13].[Na+].ClCCl>O.C(OCC)C>[F:29][C:10]([F:9])([S:25]([O-:28])(=[O:26])=[O:27])[CH:11]([O:16][C:17](=[O:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:12]([F:13])([F:15])[F:14].[CH2:1]([NH+:3]([CH2:6][CH3:7])[CH2:4][CH3:5])[CH3:2]

참가 물질

7

반응물 4

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 8471TriethylamineHCID 58112889Sodium 2-benzoyloxy-1,1,3,3,3-pentafluoropropanesulfonate

생성물 1

HCID 86618176Triethylammonium 1,1,3,3,3-pentafluoro-2-(benzoyloxy)propanesulfonate수율 75%

시약·촉매·용매 2

HCID 962Water용매HCID 3283Diethyl Ether용매

실험 절차

Triethylamine was dissolved in cold water, and hydrochloric acid was added thereto to adjust the pH of the reaction liquid to fall within a range of 1 to 3. Then sodium 1,1,3,3,3-pentafluoro-2-(benzoyloxy)propanesulfonate and dichloromethane were added thereto and stirred. The separated organic layer was washed with water, and dichloromethane was removed under reduced pressure from the washed organic layer. To the residue thus obtained, diethyl ether was added for recrystallization. The resultant was filtrated and dried to obtain a desired product at a yield of 75%.

후처리

  1. customthe pH of the reaction liquid
  2. washThe separated organic layer was washed with water, and dichloromethane
  3. customwas removed under reduced pressure from the washed organic layer
  4. customTo the residue thus obtained
  5. filtrationThe resultant was filtrated
  6. customdried

출처 및 근거

ORD 기록
ord-9c58d534780a4f299c49d84e8b761102
출처 데이터셋
uspto-grants-2011_01
특허 번호
US07871761B2

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