4-Morpholinecarbonyl chloride → HCID 178461372, 화합물

HRID 253925

반응식

HRID 253925 반응식
[Cl:1][C:2]1[S:6][C:5]([NH:7][C:8](=[O:23])[N:9]([C@H:16]2[CH2:21][CH2:20][C@H:19]([CH3:22])[CH2:18][CH2:17]2)[CH:10]2[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]2)=[N:4][CH:3]=1.[N:24]1([C:30](Cl)=[O:31])[CH2:29][CH2:28][O:27][CH2:26][CH2:25]1>>[Cl:1][C:2]1[S:6][C:5]([NH:7][C:8](=[O:23])[N:9]([C@H:16]2[CH2:21][CH2:20][C@H:19]([CH3:22])[CH2:18][CH2:17]2)[CH:10]2[CH2:11][CH2:12][N:13]([C:30]([N:24]3[CH2:29][CH2:28][O:27][CH2:26][CH2:25]3)=[O:31])[CH2:14][CH2:15]2)=[N:4][CH:3]=1

참가 물질

3

반응물 2

HCID 848104-Morpholinecarbonyl chlorideHCID 178461370HCID 178461370, 화합물

생성물 1

HCID 178461372HCID 178461372, 화합물

실험 절차

Prepared in a similar manner to Example 554 using 3-(5-chloro-thiazol-2-yl)-1-(trans-4-methyl-cyclohexyl)-1-piperidin-4-yl-urea and 4-morpholinecarbonyl chloride

출처 및 근거

ORD 기록
ord-3a998cf9561845c2b18bbe14cf7de645
출처 데이터셋
uspto-grants-2011_01
특허 번호
US07872139B2

연결된 노트

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