Ethylenediamine → 2-(2-Chloro-6-iodo-benzyl)-4,5-dihydro-1H-imidazole

반응식

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([I:8])[C:3]=1[CH:9]=[C:10](Br)Br.[CH2:13]([NH2:16])[CH2:14][NH2:15]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([I:8])[C:3]=1[CH2:9][C:10]1[NH:15][CH2:14][CH2:13][N:16]=1

참가 물질

반응물 2

HCID 3301Ethylenediamine

HCID 589518951-Chloro-2-(2,2-dibromoethenyl)-3-iodobenzene

생성물 1

HCID 247798462-(2-Chloro-6-iodo-benzyl)-4,5-dihydro-1H-imidazole

실험 절차

2-(2-Chloro-6-iodo-benzyl)-4,5-dihydro-1H-imidazole was prepared from 1-chloro-2-(2,2-dibromo-vinyl)-3-iodo-benzene and ethylenediamine in analogy to Example 1e): light yellow crystals; MS (ISP): 323.1 ([M+H]+, 35%), 321.4 ([M+H]+, 100%).

출처 및 근거

ORD 기록: ord-8b0756f7c2504dc5b60aef2714312e07
출처 데이터셋: uspto-grants-2011_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07875645B2

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