Ethylenediamine → 2-(2-Ethyl-3,6-difluoro-benzyl)-4,5-dihydro-1H-imidazole

HRID 254573노트

반응식

HRID 254573 반응식
Br[C:2](Br)=[CH:3][C:4]1[C:9]([CH2:10][CH3:11])=[C:8]([F:12])[CH:7]=[CH:6][C:5]=1[F:13].[CH2:15]([NH2:18])[CH2:16][NH2:17]>>[CH2:10]([C:9]1[C:8]([F:12])=[CH:7][CH:6]=[C:5]([F:13])[C:4]=1[CH2:3][C:2]1[NH:17][CH2:16][CH2:15][N:18]=1)[CH3:11]

참가 물질

3

반응물 2

HCID 3301EthylenediamineHCID 589518562-(2,2-Dibromo-vinyl)-3-ethyl-1,4-difluoro-benzene

생성물 1

HCID 589517482-(2-Ethyl-3,6-difluoro-benzyl)-4,5-dihydro-1H-imidazole

실험 절차

2-(2-Ethyl-3,6-difluoro-benzyl)-4,5-dihydro-1H-imidazole was prepared from 2-(2,2-dibromo-vinyl)-3-ethyl-1,4-difluoro-benzene and ethylenediamine in analogy to Example 1e): yellow crystals; MS (ISP): 225.3 ([M+H]+, 100%).

출처 및 근거

ORD 기록
ord-d31e599ce3fe4b8a9de51e3c0168bd59
출처 데이터셋
uspto-grants-2011_01
특허 번호
US07875645B2

반응 노트

불러오는 중…