4-Methoxy-2-nitrobenzoic acid → 2-Amino-4-methoxybenzoic acid
반응식
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=[O:8])=[C:5]([N+:12]([O-])=O)[CH:4]=1>[Pd].CO>[NH2:12][C:5]1[CH:4]=[C:3]([O:2][CH3:1])[CH:11]=[CH:10][C:6]=1[C:7]([OH:9])=[O:8]참가 물질
4
실험 절차
4-Methoxy-2-nitrobenzoic acid (3 g, 16.4 mmol) was hydrogenated over palladium on carbon (10%, 300 mg) in methanol (80 mL) at room temperature and normal pressure for 18 hours. The reaction mixture was filtered through celite and concentrated to dryness under reduce pressure to give 2.50 g (100%) of the product as a colorless solid.
후처리
- filtrationThe reaction mixture was filtered through celite and
- concentrationconcentrated to dryness
출처 및 근거
- ORD 기록
- ord-f8f4666ef20642c2a03ae86bb6637376
- 출처 데이터셋
- uspto-grants-2011_01
- 특허 번호
- US07875715B2
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