Potassium Nitrate → N-(3-formyl-4-nitrophenyl)acetamide

HRID 256183

반응식

HRID 256183 반응식
[N+:1]([O-:4])([O-])=[O:2].[K+].[CH:6]([C:8]1[CH:9]=[C:10]([NH:14][C:15](=[O:17])[CH3:16])[CH:11]=[CH:12][CH:13]=1)=[O:7]>S(=O)(=O)(O)O>[CH:6]([C:8]1[CH:9]=[C:10]([NH:14][C:15](=[O:17])[CH3:16])[CH:11]=[CH:12][C:13]=1[N+:1]([O-:4])=[O:2])=[O:7]

참가 물질

4

반응물 2

HCID 24434Potassium NitrateHCID 256849N-(3-formylphenyl)acetamide

생성물 1

HCID 13987601N-(3-formyl-4-nitrophenyl)acetamide수율 48.8%

시약·촉매·용매 1

HCID 1118Sulfuric Acid용매2회

반응 조건

온도
5 °C

실험 절차

A solution of potassium nitrate (6.2 g, 61 mmol) in sulfuric acid (30 mL) was added dropwise to stirred solution of N-(3-formylphenyl)acetamide (10.0 g, 61 mmol) in sulfuric acid (120 mL) maintained at 5° C. After 2 hours, the reaction mixture was poured onto ice water (500 mL) and filtered to give N-(3-formyl-4-nitrophenyl)acetamide (6.2 g, 48%) mp 131°-135° C., used without further purification.

후처리

  1. additionthe reaction mixture was poured onto ice water (500 mL)
  2. filtrationfiltered

출처 및 근거

ORD 기록
ord-d972c48809d24f6790d4889bc1c8c1e7
출처 데이터셋
uspto-grants-1987_10
특허 번호
US04701459

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