Sodium borohydride → (2,2,5,5-Tetramethylcyclopentyl)methanol

HRID 256245노트

반응식

HRID 256245 반응식
[CH3:1][C:2]1([CH3:11])[CH2:6][CH2:5][C:4]([CH3:8])([CH3:7])[CH:3]1[CH:9]=[O:10].[BH4-].[Na+]>C(O)C>[CH3:1][C:2]1([CH3:11])[CH2:6][CH2:5][C:4]([CH3:7])([CH3:8])[CH:3]1[CH2:9][OH:10]

참가 물질

4

반응물 2

HCID 4311764Sodium borohydrideHCID 9793878Cyclopentanecarboxaldehyde, 2,2,5,5-tetramethyl-

생성물 1

HCID 13629260(2,2,5,5-Tetramethylcyclopentyl)methanol

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

2,2,5,5-Tetramethylcyclopentane-1-carboxaldehyde is dissolved in 95% ethanol and sodium borohydride is added. After 24 hours, the reaction is quenched with 1M HCl and extracted with ether. The extract is washed, dried over MgSO4 and evaporated to yield 2,2,5,5-tetramethyl-1-cyclopentylmethanol.

후처리

  1. customthe reaction is quenched with 1M HCl
  2. extractionextracted with ether
  3. washThe extract is washed
  4. dry with materialdried over MgSO4
  5. customevaporated

출처 및 근거

ORD 기록
ord-b116a7274c60435fa7d0f6ad586f3ec5
출처 데이터셋
uspto-grants-1987_10
특허 번호
US04701552

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