Sodium Carbonate → HCID 20163826, 화합물

HRID 256459노트

반응식

HRID 256459 반응식
C(=O)([O-])[O-].[Na+].[Na+].Cl.[NH2:8][OH:9].[CH3:10][C:11]1[CH:12]=[C:13]([CH:16]=[CH:17][CH:18]=1)[CH2:14]Br>CN(C)C=O>[CH3:10][C:11]1[CH:12]=[C:13]([CH:16]=[CH:17][CH:18]=1)[CH2:14][N:8]([CH2:10][C:11]1[CH:18]=[CH:17][CH:16]=[C:13]([CH3:14])[CH:12]=1)[OH:9]

참가 물질

5

반응물 3

HCID 10340Sodium CarbonateHCID 12099m-Xylyl bromideHCID 443297Hydroxyamine hydrochloride

생성물 1

HCID 20163826HCID 20163826, 화합물수율 49.4%

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

The procedure of Example 1 is repeated using 21.2 g of sodium carbonate, 3.47 g of hydroxylamine hydrochloride and 18.51 g m-methylbenzyl bromide in 75 ml of dimethylformamide. Recrystallization from ethanol affords 5.95 g of the title hydroxylamine as a white solid, mp 70°-73° C.

후처리

  1. customRecrystallization from ethanol

출처 및 근거

ORD 기록
ord-50f18c8cc8b24611a33b37489303db81
출처 데이터셋
uspto-grants-1987_10
특허 번호
US04703073

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