1-Decanol → Decyl lactate

HRID 256794

반응식

HRID 256794 반응식
[C:1]([O:6][CH3:7])(=[O:5])[CH:2]([CH3:4])[OH:3].[CH2:8](O)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]C.[OH-].[Na+]>OS(O)(=O)=O.CO>[C:1]([O:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])(=[O:5])[CH:2]([CH3:4])[OH:3]

참가 물질

6

반응물 3

HCID 81741-DecanolHCID 11040Methyl LactateHCID 14798Sodium Hydroxide

생성물 1

HCID 347720Decyl lactate수율 180.9%

시약·촉매·용매 2

HCID 1118Sulfuric Acid촉매HCID 887Methanol용매

실험 절차

A 250 mL round bottom flask equipped with a spin bar and a distillation column was charged with 100 g (0.96 moles) of methyl lactate, 304.1 g (1.92 moles) of decyl alcohol, and 500 mg of H2SO4. The reaction was heated until methanol formation ceased. The reaction was then neutralized with 0.1N NaOH (100 mL) and extracted with ether. The organic layer was dried over MgSO4, filtered and dried in vacuo to give 400 g of crude mixture. The fractional distillation was carried out three times to give 98.5 g (45% yield, 100% pure by GC) of a clear colorless oil.

후처리

  1. customA 250 mL round bottom flask equipped with a spin bar
  2. distillationa distillation column
  3. extractionextracted with ether
  4. dry with materialThe organic layer was dried over MgSO4
  5. filtrationfiltered
  6. customdried in vacuo

출처 및 근거

ORD 기록
ord-2f1662f043fa4ee182792689b288e74b
출처 데이터셋
uspto-grants-1993_11
특허 번호
US05260051

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