Methyl iodide → 3-(4-Chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide

HRID 256947노트

반응식

HRID 256947 반응식
[Cl:1][C:2]1[C:3]([C:7]2[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=2)=[N:4][S:5][N:6]=1.[CH3:13][I:14]>CC(C)=O>[I-:14].[Cl:1][C:2]1[C:3]([C:7]2[CH:8]=[N+:9]([CH3:13])[CH:10]=[CH:11][CH:12]=2)=[N:4][S:5][N:6]=1

참가 물질

4

반응물 2

HCID 6328Methyl iodideHCID 104881643-Chloro-4-(pyridin-3-yl)-1,2,5-thiadiazole

생성물 1

HCID 190753343-(4-Chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide수율 100.1%

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

A solution of 3-(4-chloro-1,2,5-thiadiazol-3-yl)pyridine (1.98 g, 10 mmol) and methyl iodide (4.25 g, 30 mmol) in acetone (10 ml) was stirred at room temperature for 16 h. The precipitate was collected by filtration to yield 3.40 g (100%) of the title compound.

후처리

  1. filtrationThe precipitate was collected by filtration

출처 및 근거

ORD 기록
ord-7c33618b64b94ebdad058090f49245ac
출처 데이터셋
uspto-grants-1993_11
특허 번호
US05260311

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