1-Hydroxymethyl-2,3,3-trimethyl-cyclohexa-1,5-diene → 1-Hydroxymethyl-2,3,3-trimethyl-cyclohex-6-ene

HRID 25890노트

반응식

HRID 25890 반응식
[OH:1][CH2:2][C:3]1[CH:8]=[CH:7][CH2:6][C:5]([CH3:10])([CH3:9])[C:4]=1[CH3:11]>C(O)C.[Ni]>[OH:1][CH2:2][C:3]1[CH:4]([CH3:11])[C:5]([CH3:10])([CH3:9])[CH2:6][CH2:7][CH:8]=1

참가 물질

4

반응물 1

HCID 205694331-Hydroxymethyl-2,3,3-trimethyl-cyclohexa-1,5-diene

생성물 1

HCID 213256291-Hydroxymethyl-2,3,3-trimethyl-cyclohex-6-ene수율 91.6%

시약·촉매·용매 2

HCID 935Nickel촉매HCID 702Ethanol용매

실험 절차

30.4 g of 1-hydroxymethyl-2,3,3-trimethyl-cyclohexa-1,5-diene were hydrogenated at 10°-12° in the presence of 1g of Raney-nickel in 300 ml of ethanol. 3.95 l of hydrogen were then absorbed within 2.5 h. A filtration followed by evaporation and distillation gave 28.2 g of 1-hydroxymethyl-2,3,3-trimethyl-cyclohex-6-ene. nD = 1.4862, d20 = 9.9447

후처리

  1. custom3.95 l of hydrogen were then absorbed within 2.5 h
  2. filtrationA filtration
  3. customfollowed by evaporation and distillation

출처 및 근거

ORD 기록
ord-91f4dcac6ae64b8d866b0c8e8c0a5112
출처 데이터셋
uspto-grants-1979_04
특허 번호
US04147672

반응 노트

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