Suprofen → p-(2-Thenoyl)hydratropoyl chloride

HRID 258913

반응식

HRID 258913 반응식
[C:1]1([C:6]([C:8]2[CH:18]=[CH:17][C:11]([CH:12]([CH3:16])[C:13](O)=[O:14])=[CH:10][CH:9]=2)=[O:7])[S:5][CH:4]=[CH:3][CH:2]=1.S(Cl)([Cl:21])=O>C1C=CC=CC=1>[C:1]1([C:6]([C:8]2[CH:18]=[CH:17][C:11]([CH:12]([CH3:16])[C:13]([Cl:21])=[O:14])=[CH:10][CH:9]=2)=[O:7])[S:5][CH:4]=[CH:3][CH:2]=1

참가 물질

4

반응물 2

HCID 5359SuprofenHCID 24386Thionyl Chloride

생성물 1

HCID 11747905p-(2-Thenoyl)hydratropoyl chloride

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

A mixture of 5.2 parts of p-(2-thenoyl)hydratropic acid, 4.8 parts of thionyl chloride and 32 parts of anhydrous benzene is stirred and refluxed for 3h. 30. The reaction mixture is evaporated and the residue is evaporated once more from benzene, yielding p-(2-thenoyl)hydratropoyl chloride as a residue.

후처리

  1. temperaturerefluxed for 3h
  2. customThe reaction mixture is evaporated
  3. customthe residue is evaporated once more from benzene

출처 및 근거

ORD 기록
ord-6b9439048f53451e9dbe69fab35877a6
출처 데이터셋
uspto-grants-1977_07
특허 번호
US04035376

연결된 노트

불러오는 중…