Hydrochloric Acid → Dimethylmalonyl Dichloride

HRID 258971

반응식

HRID 258971 반응식
[CH3:1][C:2]([CH3:9])([C:6](O)=[O:7])[C:3](O)=[O:4].S(Cl)([Cl:12])=O.[ClH:14].S(=O)=O>>[CH3:1][C:2]([CH3:9])([C:6]([Cl:12])=[O:7])[C:3]([Cl:14])=[O:4]

참가 물질

5

반응물 4

HCID 313Hydrochloric AcidHCID 1119Sulfur DioxideHCID 11686Dimethylmalonic acid2회HCID 24386Thionyl Chloride

생성물 1

HCID 4523180Dimethylmalonyl Dichloride

실험 절차

To a 500 ml. one-necked flask equipped with reflux condenser with drying tube, is added 50 grams (0.38 mole) dimethylmalonic acid (Aldrich Chemical Co.) and 300 ml. thionyl chloride. The mixture is heated to reflux for about 1 hour during which time the dimethylmalonic acid is dissolved and hydrogen chloride and sulfur dioxide are evolved. The unreacted thionyl chloride is removed by distillation under reduced pressure. The residue is recrystallized twice from cyclohexane to yield a white solid, M.P. 186°-187° C.

후처리

  1. customone-necked flask equipped
  2. temperaturewith reflux condenser
  3. customwith drying tube
  4. temperatureThe mixture is heated
  5. dissolutionis dissolved
  6. customThe unreacted thionyl chloride is removed by distillation under reduced pressure
  7. customThe residue is recrystallized twice from cyclohexane
  8. customto yield a white solid, M.P. 186°-187° C.

출처 및 근거

ORD 기록
ord-38581de9b1114be4935b945dafac826a
출처 데이터셋
uspto-grants-1977_07
특허 번호
US04035437

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