Hydrochloric Acid → ((2-Aminoethyl)thio)acetic acid, methyl ester, hydrochloride

HRID 258992노트

반응식

HRID 258992 반응식
[NH2:1][CH2:2][CH2:3][S:4][CH2:5][C:6]([OH:8])=[O:7].[CH3:9]OC(OC)(C)C.[ClH:16]>CO>[ClH:16].[CH3:9][O:7][C:6]([CH2:5][S:4][CH2:3][CH2:2][NH2:1])=[O:8]

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 64952,2-DimethoxypropaneHCID 4474780HCID 4474780, 화합물

생성물 1

HCID 170337((2-Aminoethyl)thio)acetic acid, methyl ester, hydrochloride

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

13.5 g of S-(β-aminoethyl)mercaptoacetic acid and 10.8 g of 2,2-dimethoxy propane are added, successively, to a solution of 7.3 g of gaseous hydrochloric acid in 20 cc of methanol. The solution is permitted to stand for 12 hours at ambient temperature. The flakes formed (17.5 g) are filtered and washed with ethyl acetate. Fusion point = 100° C.

후처리

  1. customThe flakes formed (17.5 g)
  2. filtrationare filtered
  3. washwashed with ethyl acetate
  4. customFusion point = 100° C.

출처 및 근거

ORD 기록
ord-80dbc8443be6466a94408aff2a12ece9
출처 데이터셋
uspto-grants-1977_07
특허 번호
US04035492

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