N-bromobutanimide → 3-Bromo-4,5,6-trimethoxyphthalide
반응식
[CH3:1][O:2][C:3]1[C:12]([O:13][CH3:14])=[C:11]([O:15][CH3:16])[CH:10]=[C:9]2[C:4]=1[CH2:5][O:6][C:7]2=[O:8].[Br:17]N1C(=O)CCC1=O.N(CCCC#N)=NCCCC#N>C(Cl)(Cl)(Cl)Cl>[Br:17][CH:5]1[C:4]2[C:9](=[CH:10][C:11]([O:15][CH3:16])=[C:12]([O:13][CH3:14])[C:3]=2[O:2][CH3:1])[C:7](=[O:8])[O:6]1참가 물질
5
실험 절차
4,5,6-Trimethoxyphthalide (11.4 gms; 0.05 mole), N-bromosuccinimide (8.9 gms; 0.05 mole) and azobisbutyronitrile (0.1 gms) were refluxed gently in dry carbon tetrachloride (200 mls) for 2 hours. The solution was cooled, the succinimide filtered off and the solvent removed in vacuo, leaving a yellowish solid which fumed in the air.
후처리
- temperatureThe solution was cooled
- filtrationthe succinimide filtered off
- customthe solvent removed in vacuo
- customleaving a yellowish solid which
출처 및 근거
- ORD 기록
- ord-135b9d78d4b64f47ac018ecbeec80aeb
- 출처 데이터셋
- uspto-grants-1977_07
- 특허 번호
- US04036829
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