Hydrochloric Acid → HCID 20356988, 화합물

반응식

[CH2:1]1[O:13][C:12]2[CH:11]=[C:10]3[C:5]([C:6](=[O:24])[C:7]([C:19]([O:21]CC)=[O:20])=[CH:8][N:9]3[CH2:14][C:15]([F:18])([F:17])[F:16])=[CH:4][C:3]=2[O:2]1.Cl>>[CH2:1]1[O:13][C:12]2[CH:11]=[C:10]3[C:5]([C:6](=[O:24])[C:7]([C:19]([OH:21])=[O:20])=[CH:8][N:9]3[CH2:14][C:15]([F:18])([F:17])[F:16])=[CH:4][C:3]=2[O:2]1

참가 물질

반응물 2

HCID 313Hydrochloric Acid

HCID 86734955HCID 86734955, 화합물

생성물 1

HCID 20356988HCID 20356988, 화합물

실험 절차

A mixture of 1 g. of the ethyl ester obtained from Example 3 and 40 ml. of 6N. hydrochloric acid was heated under reflux for 11/2 hours. The mixture was cooled and the solid product was collected by filtration and washed with water and dried under reduced pressure, m.p. 323°-5° C. (dec.).

후처리

additionA mixture of 1 g
temperatureunder reflux for 11/2 hours
temperatureThe mixture was cooled
filtrationthe solid product was collected by filtration
washwashed with water
customdried under reduced pressure, m.p. 323°-5° C. (dec.)

출처 및 근거

ORD 기록: ord-e256dc4aa1df43379ff3131c713ff48c
출처 데이터셋: uspto-grants-1977_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04036962

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