Sodium Hydroxide → 4-Amino-5,6-dihydro-1-benzothiophen-7(4H)-one

HRID 259341노트

반응식

HRID 259341 반응식
Cl.[O:2]=[C:3]1[C:8]2[S:9][CH:10]=[CH:11][C:7]=2[CH:6]([NH2:12])[CH2:5][CH2:4]1.[OH-].[Na+]>O>[O:2]=[C:3]1[C:8]2[S:9][CH:10]=[CH:11][C:7]=2[CH:6]([NH2:12])[CH2:5][CH2:4]1

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 233477954,5,6,7-Tetrahydro-7-oxobenzo[b]thiophen-4-amine hydrochloride

생성물 1

HCID 233477964-Amino-5,6-dihydro-1-benzothiophen-7(4H)-one

시약·촉매·용매 1

HCID 962Water용매

실험 절차

The free amine is obtained by neutralizing the amine hydrochloride in water with sodium hydroxide solution. It is separated by extraction with CHCl3 and removal of the CHCl3 in vacuo affords 4,5,6,7-tetrahydro-7-oxobenzo[b]thiophen-4-amine.

후처리

  1. customIt is separated by extraction with CHCl3 and removal of the CHCl3 in vacuo

출처 및 근거

ORD 기록
ord-d354b11bc4894fd8a8ebc99a9b71a2f8
출처 데이터셋
uspto-grants-1977_07
특허 번호
US04036979

반응 노트

불러오는 중…