Hydrochloric Acid → HCID 21422240, 화합물

HRID 259531

반응식

HRID 259531 반응식
[Cl:1][S:2]([OH:5])(=[O:4])=[O:3].[CH3:6][O:7][C:8]1[CH:9]=[C:10]([CH3:16])[CH:11]=[CH:12][C:13]=1[O:14][CH3:15].Cl>C1C=CC=CC=1>[S:2]([Cl:1])([OH:5])(=[O:4])=[O:3].[CH3:16][C:10]1[CH:9]=[C:8]([O:7][CH3:6])[C:13]([O:14][CH3:15])=[CH:12][CH:11]=1

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 24638Chlorosulfonic acidHCID 681263,4-Dimethoxytoluene

생성물 1

HCID 21422240HCID 21422240, 화합물

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

23.2 gm (0.2 mol) of chlorosulfonic acid were slowly added dropwise to 15.2 gm (0.1 mol) of 3,4-dimethoxy-toluene at about - 10° C., while stirring and cooling. Afterwards, the mixture was allowed to warm to room temperature, and was then stirred until the evolution of hydrogen chloride ceased. The reaction mixture was poured over ice, and the precipitated sulfochloride was extracted with ether. The organic phase was successively washed with sodium bicarbonate solution and water, and then evaporated to dryness in vacuo. A turbid oil was obtained as a residue, which solidified after cooling. Rf -value (benzene): 0.5.

후처리

  1. temperaturecooling
  2. additionThe reaction mixture was poured over ice
  3. extractionthe precipitated sulfochloride was extracted with ether
  4. washThe organic phase was successively washed with sodium bicarbonate solution and water
  5. customevaporated to dryness in vacuo
  6. customA turbid oil was obtained as a residue
  7. temperatureafter cooling

출처 및 근거

ORD 기록
ord-8da7098edd54451688031f7be482a051
출처 데이터셋
uspto-grants-1977_07
특허 번호
US04038407

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