Ammonium Acetate → Ethyl 3-amino-2-chloro-4-methyl-2-pentenoate

HRID 259803노트

반응식

HRID 259803 반응식
[Cl:1][CH:2]([C:8](=O)[CH:9]([CH3:11])[CH3:10])[C:3]([O:5][CH2:6][CH3:7])=[O:4].C([O-])(=O)C.[NH4+:17]>CO>[NH2:17][C:8]([CH:9]([CH3:11])[CH3:10])=[C:2]([Cl:1])[C:3]([O:5][CH2:6][CH3:7])=[O:4]

참가 물질

4

반응물 2

HCID 517165Ammonium AcetateHCID 9877606Ethyl 2-chloro-4-methyl-3-oxopentanoate

생성물 1

HCID 86749531Ethyl 3-amino-2-chloro-4-methyl-2-pentenoate수율 88%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

59.5 g (0.31 mol) of ethyl 2-chloro-4-methyl-3-oxo-pentanoate are reacted with 59.8 g (0.78 mol) of ammonium acetate in 120 ml of methanol and worked up in analogy to Example 2. Yield: 88.0% [GC]

출처 및 근거

ORD 기록
ord-890cfefd4e874537ba30aac96aa2c748
출처 데이터셋
uspto-grants-1996_06
특허 번호
US05523404

반응 노트

불러오는 중…