Sodium Hydroxide → N,N-Dibenzyl-L-phenylalanine

HRID 259827노트

반응식

HRID 259827 반응식
Cl.[CH2:2]([N:9]([CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[C@H:10]([C:18]([OH:20])=[O:19])[CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[OH-].[Na+]>C(Cl)Cl>[CH2:21]([N:9]([CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1)[C@H:10]([C:18]([OH:20])=[O:19])[CH2:11][C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)[C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 69745698HCID 69745698, 화합물

생성물 1

HCID 10980880N,N-Dibenzyl-L-phenylalanine

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

N,N-Dibenzyl-L-phenylalanine hydrochloride (50 g) was dissolved in methylene chloride (500 ml), and an aqueous solution of sodium hydroxide (sodium hydroxide 6 g, water 500 ml) was added thereto. After stirring the mixture for 30 minutes, it was partitioned, and the organic layer was dried over magnesium sulfate and concentrated under reduced pressure to give N,N-dibenzyl-L-phenylalanine as an oily substance.

후처리

  1. customit was partitioned
  2. dry with materialthe organic layer was dried over magnesium sulfate
  3. concentrationconcentrated under reduced pressure

출처 및 근거

ORD 기록
ord-5bd915c8abba4ef192747210afc6e22e
출처 데이터셋
uspto-grants-1996_06
특허 번호
US05523410

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