Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylthiocarbamoyl chloride → Dimethylthiocarbamoyl valine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylthiocarbamoyl chloride | HCID 27871 | — |
| 반응물 | l-Valine, ethyl ester | HCID 87182 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | Dimethylthiocarbamoyl valine | HCID 53885838 | — |
반응 단계
Valine ethyl ester (0.0028 mol) in 10 ml acetonitrile was reacted with dimethylthiocarbamoyl chloride (0.0056 mol) at 50° C. for 2 hours. Solvent acetonitrile was removed by rotary evaporation. Trifluoroacetic acid (10 ml) was added and the mixture stirred at room temperature for 15 min. The trifluoroacetic acid was removed by rotary evaporation. The residue was dissolved in water and analyzed by FAB/MS. The expected product, dimethylthiocarbamoyl valine (MH+=205), was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05525707 |
| 출처 데이터셋 | uspto-grants-1996_06 |
| ORD ID | ord-7c3f4ac9582a492d88c902c8d1fa939d |
| 출처 메모 | uspto-grants-1996_06 |