Pyridine → Cotinine

HRID 260253

반응식

HRID 260253 반응식
[CH3:1][N:2]1[C:6](=[O:7])[C@H:5](O)[CH2:4][C@H:3]1[C:9]1[CH:14]=[CH:13][CH:12]=[N:11][CH:10]=1.C1(=O)OC(=O)CC1.N1C=CC=CC=1>CN(C)C=O>[CH3:1][N:2]1[C:6](=[O:7])[CH2:5][CH2:4][C@H:3]1[C:9]1[CH:14]=[CH:13][CH:12]=[N:11][CH:10]=1

참가 물질

5

반응물 3

HCID 1049PyridineHCID 7922Succinic anhydrideHCID 1079633'-Hydroxycotinine, trans-

생성물 1

HCID 854019Cotinine

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

Cotinine hemisuccinate was prepared by dissolving 19 mg of trans-3'-hydroxycotinine in 1 ml of dimethylformamide (Aldrich). 21 mg of succinic anhydride (Aldrich) were added, followed by 15 μl of pyridine (Aldrich). The mixture was incubated overnight at 45° C.

출처 및 근거

ORD 기록
ord-7c2cd0ad0eb24c1c8ca3ae468fdcc9cc
출처 데이터셋
uspto-grants-1996_06
특허 번호
US05527686

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