2-Mercaptoethanol → 2-(6-Carboxyhexyl)-4-(2-hydroxyethylthio)cyclopent-2-en-1-one

HRID 261397

반응식

HRID 261397 반응식
[C:1]([CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]1[C:11](=[O:16])[CH2:12][CH:13](O)[CH:14]=1)([OH:3])=[O:2].[SH:17][CH2:18][CH2:19][OH:20].C[O-].[Na+]>CO>[C:1]([CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]1[C:11](=[O:16])[CH2:12][CH:13]([S:17][CH2:18][CH2:19][OH:20])[CH:14]=1)([OH:3])=[O:2]

참가 물질

5

반응물 3

HCID 15672-MercaptoethanolHCID 3690897ACMC-20apjzHCID 10942334Sodium Methoxide

생성물 1

HCID 233466542-(6-Carboxyhexyl)-4-(2-hydroxyethylthio)cyclopent-2-en-1-one

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

In the manner of Example 281 a methanol solution of 2-(6-carboxyhexyl)-4-hydroxycyclopent-2-en-1-one [Prostaglandins, 3, 921 (1973)] and β-mercaptoethanol is treated with sodium methoxide solution, acidified, concentrated, and extracted to provide the subject compound as an oil.

후처리

  1. concentrationconcentrated
  2. extractionextracted

출처 및 근거

ORD 기록
ord-30160fcc15e5467ca5ce4ce942634e16
출처 데이터셋
uspto-grants-1979_08
특허 번호
US04165331

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