Aniline → N-Phenylphthalimide

반응식

[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:8]1(=O)[O:13][C:11](=[O:12])[C:10]2=[CH:14][CH:15]=[CH:16][CH:17]=[C:9]12>>[C:2]1([N:1]2[C:11](=[O:12])[C:10]3=[CH:14][CH:15]=[CH:16][CH:17]=[C:9]3[C:8]2=[O:13])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

반응물 2

HCID 6115Aniline

HCID 6811Phthalic Anhydride

생성물 1

HCID 68215N-Phenylphthalimide

실험 절차

Phenylphthalimidine of the formula (II) [L. Butula, D. Kolbah and I. Butula, Croat. Chem. Acta, 44 (4), 481, (1972),], which is a starting compound of the method of this invention, may be produced according to conventional methods. For example, Compound (II) is preferably produced in a high yield by heating aniline and phthalic anhydride in the absence of a solvent to give N-phenylphthalimide in an almost quantitative yield, and then subjecting the obtained N-phenylphthalimide to reduction with zinc and acetic acid.

후처리

custommay be produced
customa high yield

출처 및 근거

ORD 기록: ord-aa68276ba25340a49269a3844050aa72
출처 데이터셋: uspto-grants-1979_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04166125

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