Aniline → N-Phenylphthalimide

HRID 261521

반응식

HRID 261521 반응식
[C:1]1(=[O:11])[O:6][C:4](=O)[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.[NH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>O>[C:13]1([N:12]2[C:1](=[O:11])[C:2]3=[CH:10][CH:9]=[CH:8][CH:7]=[C:3]3[C:4]2=[O:6])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

참가 물질

4

반응물 2

HCID 6115AnilineHCID 6811Phthalic Anhydride

생성물 1

HCID 68215N-Phenylphthalimide수율 97.8%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A mixture of phthalic anhydride (19 g) and aniline (14 g) is heated at 140° to 145° C. for 50 minutes, and to the reaction mixture is added water (50 ml). The resulting powder is collected by filtration, washed with 10% aqueous potassium carbonate solution (50 ml) and water (100 ml), and dried to give colorless powder (28 g, 97%). Recrystallization from acetic acid gives colorless needles.

후처리

  1. temperatureis heated at 140° to 145° C. for 50 minutes
  2. filtrationThe resulting powder is collected by filtration
  3. washwashed with 10% aqueous potassium carbonate solution (50 ml) and water (100 ml)
  4. customdried

출처 및 근거

ORD 기록
ord-e7a966f74d854f029309b5b4bd32bdb5
출처 데이터셋
uspto-grants-1979_08
특허 번호
US04166125

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