Hydrochloric Acid → 3-Amino-7-benzamidoheptan-2-one hydrochloride

HRID 261618노트

반응식

HRID 261618 반응식
C([NH:9][CH:10]([CH2:14][CH2:15][CH2:16][CH2:17][NH:18][C:19](=[O:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[C:11](=[O:13])[CH3:12])(=O)C1C=CC=CC=1.[ClH:27]>>[ClH:27].[NH2:9][CH:10]([CH2:14][CH2:15][CH2:16][CH2:17][NH:18][C:19](=[O:26])[C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1)[C:11](=[O:13])[CH3:12]

참가 물질

3

반응물 2

HCID 313Hydrochloric AcidHCID 127698383,7-Dibenzamidoheptan-2-one

생성물 1

HCID 203945683-Amino-7-benzamidoheptan-2-one hydrochloride수율 34.2%

실험 절차

3,7-Dibenzamidoheptan-2-one (91.11 g, 0.258 mol) was hydrolysed in a sealed tube with concentrated HCl for 3 hours at 160° (oil bath). The solution was extracted with ether and evaporated to dryness to give 3-amino-7-benzamidoheptan-2-one hydrochloride (25.01 g, 34.2%).

후처리

  1. extractionThe solution was extracted with ether
  2. customevaporated to dryness

출처 및 근거

ORD 기록
ord-0dfa7767110e41af95b6413b4d86f4d6
출처 데이터셋
uspto-grants-1979_08
특허 번호
US04166184

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