Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → (4-bromophenyl)(1H-imidazol-2-yl)phenylmethanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | alpha-(p-Bromophenyl)-alpha-phenyl-1-(toluene-p-sulphonyl)imidazole-2-methanol | HCID 11838798 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | (4-bromophenyl)(1H-imidazol-2-yl)phenylmethanol | HCID 12433864 | — |
반응 단계
A mixture of 24.8 g. (0.052 mol) of α-(p-bromophenyl)-α-phenyl-1-(toluene-p-sulphonyl)imidazole-2-methanol, 160 ml. of 2 N hydrochloric acid solution (0.156 mol) and about 500 ml. of water was boiled under reflux for 5 hours. After cooling the mixture was made alkaline by addition of ammonia. The precipitated solid was collected, treated with activated carbon in boiling toluene and crystallised from toluene. Melting point of the product was 156°-158° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04152441 |
| 출처 데이터셋 | uspto-grants-1979_05 |
| ORD ID | ord-26d17c2475ad44a4a697a698d7e18002 |
| 출처 메모 | uspto-grants-1979_05 |