反应详情

A mixture of 24.8 g. (0.052 mol) of α-(p-bromophenyl)-α-phenyl-1-(toluene-p-sulphonyl)imidazole-2-methanol, 160 ml. of 2 N hydrochloric acid solution (0.156 mol) and about 500 ml. of water was boiled under reflux for 5 hours. After cooling the mixture was made alkaline by addition of ammonia. The precipitated solid was collected, treated with activated carbon in boiling toluene and crystallised from toluene. Melting point of the product was 156°-158° C.

1. additionA mixture of 24.8 g
2. temperatureunder reflux for 5 hours
3. temperatureAfter cooling the mixture
4. customThe precipitated solid was collected
5. additiontreated with activated carbon
6. customcrystallised from toluene
7. customwas 156°-158° C.