Acetic Anhydride → 4-Amino-2-hydroxymethyl-3-methoxypyridine

HRID 262480노트

반응식

HRID 262480 반응식
[N+:1]([C:4]1[CH:9]=[CH:8][N+:7]([O-])=[C:6]([CH3:11])[C:5]=1[O:12][CH3:13])([O-])=O.[H][H].C(OC(=O)C)(=[O:18])C>[Pd]>[NH2:1][C:4]1[CH:9]=[CH:8][N:7]=[C:6]([CH2:11][OH:18])[C:5]=1[O:12][CH3:13]

참가 물질

5

반응물 3

HCID 7918Acetic AnhydrideHCID 151634563-Methoxy-2-methyl-4-nitropyridine 1-oxideHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 204742014-Amino-2-hydroxymethyl-3-methoxypyridine

시약·촉매·용매 1

HCID 23938Palladium촉매

실험 절차

4-Nitro-3-methoxy-2-methylpyridine N-oxide is heated in acetic anhydride and the purified product is deacetylated and reduced with hydrogen and palladium on charcoal to give 4-amino-2-hydroxymethyl-3-methoxypyridine.

출처 및 근거

ORD 기록
ord-d99774e72e494f6d998e88077c93268f
출처 데이터셋
uspto-grants-1979_05
특허 번호
US04154838

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