Methyl iodide → 2-Methylthio-5-[1-(3-pyridyl)ethyl]-4-pyrimidone
반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]([C:9]2[C:10](=[O:16])[NH:11][C:12](=[S:15])[NH:13][CH:14]=2)[CH3:8])[CH:2]=1.CI.[O-][CH2:20]C.[Na+]>C(O)C>[CH3:20][S:15][C:12]1[NH:11][C:10](=[O:16])[C:9]([CH:7]([C:3]2[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=2)[CH3:8])=[CH:14][N:13]=1참가 물질
5
실험 절차
Treatment of 5-(1-(3-pyridyl)ethyl)-2-thiouracil with methyl iodide and sodium ethoxide in ethanol at 0°, followed by acidification gave 2-methylthio-5-[1-(3-pyridyl)ethyl]-4-pyrimidone m.p. 201°-204°.
후처리
- customat 0°
출처 및 근거
- ORD 기록
- ord-d8f41b10ea964a74b11d66eea3d7d71e
- 출처 데이터셋
- uspto-grants-1979_05
- 특허 번호
- US04154834
반응 노트
불러오는 중…