반응식
[CH2:1]([Li])[CH2:2][CH2:3]C.C=O.[OH:8][CH2:9][C:10]1[N:14]2CCCCC2=[CH:12][N:11]=1>>[CH3:12][N:11]1[CH:3]=[C:2]([CH3:1])[N:14]=[C:10]1[CH2:9][OH:8]참가 물질
4
실험 절차
The reaction of 1,4-dimethylamidazole (5.65 g.) with n-butyl lithium followed by treatment with formaldehyde (according to the method described for the preparation of 3-hydroxymethyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine in Example 243) gave 1,4-dimethyl-2-hydroxymethylimidazole (2.71 g.), m.p. 125°-126° (ethyl acetate-petroleum ether).
출처 및 근거
- ORD 기록
- ord-600d33573d3948dab7ef1f782a87ba80
- 출처 데이터셋
- uspto-grants-1979_05
- 특허 번호
- US04154844
연결된 노트
불러오는 중…