Phenethylamine → N-[[3-Methoxy-2-[3-(4-morpholinyl)propoxy]phenyl]methylene]benzeneethanamine

HRID 263112

반응식

HRID 263112 반응식
[CH3:1][O:2][C:3]1[C:4]([O:11][CH2:12][CH2:13][CH2:14][N:15]2[CH2:20][CH2:19][O:18][CH2:17][CH2:16]2)=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH:6]=O.[CH2:21]([NH2:29])[CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>C1(C)C=CC=CC=1>[CH3:1][O:2][C:3]1[C:4]([O:11][CH2:12][CH2:13][CH2:14][N:15]2[CH2:20][CH2:19][O:18][CH2:17][CH2:16]2)=[C:5]([CH:6]=[N:29][CH2:21][CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH:8]=[CH:9][CH:10]=1

참가 물질

4

반응물 2

HCID 1001PhenethylamineHCID 22003483-Methoxy-2-[3-(4-morpholinyl)propoxy]benzaldehyde

생성물 1

HCID 20298672N-[[3-Methoxy-2-[3-(4-morpholinyl)propoxy]phenyl]methylene]benzeneethanamine수율 85.9%

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

3-Methoxy-2-[3-(4-morpholinyl)propoxy]benzaldehyde (42.5 g) and 18.5 g of phenethylamine are reacted in 150 ml of toluene following the procedure described in Example 1B, yielding 50.0 g of the title compound, boiling point 229°-234° C. at 0.2-0.3 mm of Hg.

출처 및 근거

ORD 기록
ord-7570d6d9087a47b5a8672c3631e77cdd
출처 데이터셋
uspto-grants-1979_05
특허 번호
US04156079

연결된 노트

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